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Did God lie to us?

The question would surprise all because why should the powerful almighty lie to Humans? The book of Genesis says the creation of God with the below list: Day 1: Light. Day 2: Atmosphere. Day 3: Dry ground & plants. Day 4: Sun, moon & stars. Day 5: Birds & sea creatures. Day 6: Land animals […]

Elephant in the dark?

The story goes on like this. A group of people do not know how an elephant looks like; in fact, the animal is new to them. So, their eyes are masked and allowed to touch and say, how an elephant looks like? Their interpretation of elephant was funny based on the portion they touched. One […]

Operation success but patient died!

We had heard Doctors saying “Operation success but patient died”. There are many reasons for this statement, the treatment / surgery might have been late, the age, immune system did not respond, drug not effective etc. This statement might have been more relevant to the failure rate of surgeries due to the operation theatre conditions. […]

Digging the graves of Devonport, England-1972.

50 years back, there was a major incident involving the manufacture of a pharmaceutical product [ 5% Dextrose, Intra Venous infusion] in Devonport near Plymouth, England. The event is remembered as “Devonport disaster”. Given the time, many working in the pharmaceutical industry have never heard about the disaster. Many died after the administration of 5% […]

Ishikawa-Fish for thought?

Overview 1.Fish bone diagram is a tool which is used to identify the root cause of the problem. The fish bone diagram is also called as Ishikawa diagram based on its pioneer Kaoru Ishikawa, a Japanese Engineering professor. He is noted for his quality management innovations and considered a key figure in the development of quality initiatives […]

How safe are Injections / infusions that are labelled as Sterile?

Concept 1.The drug injections/infusions that are manufactured in the pharmaceuticals are tested for sterility for every lot/batch. Sterility testing is performed to check the drug injections/infusions that are released to the market as “STERILE” i.e., they are free from microorganisms. Any drug injections/infusions that reach the blood system should be sterile or else the contaminated […]

Rabbits, Horse shoe crab, what next in Endotoxin?

Rabbits were used for the pyrogen testing from 1940’s and were replaced with LAL testing from 1977. For LAL testing [Bacterial endotoxins], the blood of horse shoe crabs are used to till date. LAL testing  continues to serve as an efficient and reliable safety test for human and animal injectable drugs. LAL test prevails in the pharmaceutical […]